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Case studies·Pharmaceuticals

Global Pharmaceutical — Decision Effectiveness

Rebuilding how a global pharma executive committee makes resource-allocation decisions across a crowded portfolio.

Context

A global pharmaceutical company with a wide pipeline, long investment horizons, and the usual pattern of too many promising candidates competing for the same bounded capital and attention.

Challenge

Decision meetings had become presentations of pre-cooked recommendations. The actual trade-offs between candidates were made upstream, in the sponsor's team, not in the committee. The committee ratified; it did not decide.

Approach

We rebuilt the decision mechanics. The committee saw the same evidence base — not the sponsor's filtered version. Decisions were logged with their rationale, so later outcomes could be reviewed against the reasoning at the time, not against hindsight.

A short discipline change made the biggest difference: no slide was shown without the three alternative options that had been considered and the specific reason each was rejected.

What shifted

The committee started saying no earlier and investing more into the fewer bets it kept. The sponsor behaviour changed because the incentive to pre-cook disappeared.

What shifted: the committee started making decisions, not approving them.

Client identity anonymised. Specific metrics available under NDA.

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